Exercise sparks brain changes in Parkinson's patients
NCT ID NCT05972759
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how forced and voluntary exercise change brain signals and thinking skills in 25 people with Parkinson's disease who have a brain pacemaker (DBS). Participants did one session of each exercise type while off their usual medications and DBS. The goal was to find brain patterns linked to better attention and memory, which could guide future exercise treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- forced and voluntary exercise
- What this could lead to
- If successful, this could help design better exercise programs to slow cognitive decline in Parkinson's disease.
- What could go wrong
- This is a small, early study with only 25 participants and a single exercise session, so results may not apply to long-term or broader populations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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