Exercise sparks brain changes in Parkinson's patients

NCT ID NCT05972759

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how forced and voluntary exercise change brain signals and thinking skills in 25 people with Parkinson's disease who have a brain pacemaker (DBS). Participants did one session of each exercise type while off their usual medications and DBS. The goal was to find brain patterns linked to better attention and memory, which could guide future exercise treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

forced and voluntary exercise

What this could lead to

If successful, this could help design better exercise programs to slow cognitive decline in Parkinson's disease.

What could go wrong

This is a small, early study with only 25 participants and a single exercise session, so results may not apply to long-term or broader populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States