Can a patch beat a pill? new study aims to strengthen bones in women with hormone imbalance

NCT ID NCT07010146

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study looks at whether natural estrogen given through a skin patch improves bone strength more than natural estrogen pills or a synthetic birth control patch in women aged 14–30 with functional hypothalamic amenorrhea (missed periods due to stress, low weight, or exercise). Participants take estrogen for one year, plus calcium and vitamin D, and attend four study visits. The goal is to find the best way to protect bones in this condition.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22908, United States

  • University of Virginia Medical Center

    RECRUITING

    Charlottesville, Virginia, 22903, United States

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