Experimental drug shows promise for Hard-to-Treat prostate cancer

NCT ID NCT04754425

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 study tested the drug erdafitinib in 11 men with castration-resistant prostate cancer that had spread to the bone. The goal was to see if the drug could slow the cancer and to study bone and blood markers. The trial was terminated early, so results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Erdafitinib (Balversa)

What this could lead to

If successful, this could point toward a new treatment option for men with advanced prostate cancer that has spread to the bone and stopped responding to standard hormone therapy.

What could go wrong

This trial was terminated early with only 11 participants, so results are very limited. It is unclear if erdafitinib will prove effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic carcinoma in the bone metastatic prostate carcinoma prostate cancer prostate small cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States