Soy supplement shows promise for aging brains and arteries

NCT ID NCT05741060

Ongoing Disease control Sponsor: Akira Sekikawa Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily soy-based supplement called Equol can slow down stiffening of the arteries, small blood vessel damage in the brain, and memory decline. About 369 older adults (ages 65-85) will take Equol or a placebo for two years. Researchers will measure artery stiffness, brain scans, and thinking tests to see if Equol helps protect brain health.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTERIAL STIFFNESS COGNITIVE DECLINE WHITE MATTER LESIONS

Contacts and locations

Locations

Emory University

Atlanta, Georgia, 30322, United States
University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States
Wake Forest University Health Sciences

Winston-Salem, North Carolina, 27157, United States

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