Soy supplement shows promise for aging brains and arteries

NCT ID NCT05741060

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a daily soy-based supplement called Equol can slow down stiffening of the arteries, small blood vessel damage in the brain, and memory decline. About 369 older adults (ages 65-85) will take Equol or a placebo for two years. Researchers will measure artery stiffness, brain scans, and thinking tests to see if Equol helps protect brain health.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Emory University

    Atlanta, Georgia, 30322, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina, 27157, United States