Could switching frequencies in brain stimulation help Parkinson's patients walk better?

NCT ID NCT05022147

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether alternating between high and low frequencies of deep brain stimulation (DBS) can improve walking and balance in people with Parkinson's disease. Twelve participants who already have DBS implants will try different stimulation patterns while their gait and tremor are measured. The goal is to find a better way to program DBS to reduce freezing and falls.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Deep brain stimulation (DBS) device with alternating high and low frequencies

What this could lead to

If successful, this could point toward a better way to program DBS devices to improve walking and reduce falls in Parkinson's patients.

What could go wrong

This is a very small, early-phase study with only 12 participants, so results may not apply to everyone. The approach is experimental and may not work better than standard stimulation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Disease Progression Gait Disorders, Neurologic Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States