Could switching frequencies in brain stimulation help Parkinson's patients walk better?
NCT ID NCT05022147
First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 3 times
Summary
This study tests whether alternating between high and low frequencies of deep brain stimulation (DBS) can improve walking and balance in people with Parkinson's disease. Twelve participants who already have DBS implants will try different stimulation patterns while their gait and tremor are measured. The goal is to find a better way to program DBS to reduce freezing and falls.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Deep brain stimulation (DBS) device with alternating high and low frequencies
- What this could lead to
- If successful, this could point toward a better way to program DBS devices to improve walking and reduce falls in Parkinson's patients.
- What could go wrong
- This is a very small, early-phase study with only 12 participants, so results may not apply to everyone. The approach is experimental and may not work better than standard stimulation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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