Can a diabetes drug boost heart function in obese patients?

NCT ID NCT06782139

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether enavogliflozin, a diabetes drug, can improve heart function and exercise capacity in 30 obese adults with type 2 diabetes. Participants receive either the drug or a placebo for 12 weeks, and doctors measure changes in heart blood flow and fitness. The goal is to see if the drug helps the heart work better in this high-risk group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Enavogliflozin (a drug that lowers blood sugar and may help the heart)

What this could lead to

If it works, this could show that enavogliflozin improves heart function and exercise ability in people with obesity and diabetes.

What could go wrong

This is a small, early-phase trial with only 30 people, so results may not apply to everyone. The drug may not show clear benefits over placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Korea University Anam Hospital

    RECRUITING

    Seoul, 02841, South Korea

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact