Beads that block blood flow could ease knee arthritis pain

NCT ID NCT05112926

First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study tests whether injecting tiny beads into arteries around the knee can reduce pain in people with moderate to severe knee osteoarthritis. The beads block blood flow to the painful area. Nine adults aged 40 to 80 who have not gotten relief from standard treatments are taking part. Researchers will measure pain changes and watch for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Embosphere Microspheres (tiny beads used to block blood flow)
What this could lead to
If it works, this could offer a new way to reduce knee pain without surgery or long-term medication.
What could go wrong
This is a very small, early study with only 9 people, so results may not apply widely. The procedure carries risks like pain, swelling, or damage to nearby tissue.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Miami

    Miami, Florida, 33136, United States

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Other studies related to the condition(s) this trial covers.