Could a common adult IBS drug help kids? new trial aims to find out

NCT ID NCT03339128

Recruiting now Symptom relief Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing the drug eluxadoline (Viberzi) in children aged 6 to 17 who have irritable bowel syndrome with diarrhea (IBS-D). The goal is to see if it improves stool consistency and is safe for kids. About 95 children will take either the drug or a placebo for 4 weeks, and researchers will track changes in their bathroom habits using a special scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: eluxadoline (Viberzi)
What this could lead to: If successful, this could provide a new treatment option for children with irritable bowel syndrome with diarrhea, helping to improve stool consistency and quality of life.
What could go wrong: This is an early phase 2 study with only 95 participants, so results may not apply to all children. The drug is already approved for adults, but its safety and effectiveness in kids are still unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

irritable bowel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRRITABLE BOWEL SYNDROME

Contacts and locations

Locations

Advocate Children's Hospital-Park Ridge /ID# 235388
COMPLETED

Park Ridge, Illinois, 60068, United States
Applied Research Center of Arkansas /ID# 238070
RECRUITING

Little Rock, Arkansas, 72212-4187, United States
Blackpool Teaching Hospitals NHS Foundation Trust /ID# 237273
COMPLETED

Blackpool, FY3 8NR, United Kingdom
Celen Medical Group Corp /ID# 234922
COMPLETED

Marlton, New Jersey, 08053, United States
Centrum Zdrowia MDM /ID# 237269
COMPLETED

Warsaw, Masovian Voivodeship, 00-189, Poland
Children's Ctr Digestive, US /ID# 237575
COMPLETED

Atlanta, Georgia, 30342, United States
Children's Hospital of Philadelphia - Main /ID# 234313
COMPLETED

Philadelphia, Pennsylvania, 19104-4319, United States
Cook Children's Med. Center /ID# 237537
COMPLETED

Fort Worth, Texas, 76104, United States
Copertnicus Podmiot Leczniczy Sp. z o.o. /ID# 235656
COMPLETED

Gdansk, Pomeranian Voivodeship, 80-803, Poland
Duplicate_Academisch Medisch Centrum /ID# 237117
COMPLETED

Amsterdam, North Holland, 1105 AZ, Netherlands
Duplicate_Center for Clinical Trials LLC /ID# 234630
COMPLETED

Paramount, California, 90723, United States
Duplicate_Edmonton Clinic Health Academy (ECHA) /ID# 234917
COMPLETED

Edmonton, T6G 1C9, Canada
Duplicate_Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 234311
COMPLETED

Warsaw, Masovian Voivodeship, 04-730, Poland
Duplicate_Manchester University NHS Foundation Trust /ID# 234663
COMPLETED

Manchester, Lancashire, M13 9WL, United Kingdom
Duplicate_VVCRD Research /ID# 234606
COMPLETED

Garden Grove, California, 92845, United States
Duplicate_Wellness Clinical Research /ID# 237401
COMPLETED

Miami Lakes, Florida, 33016, United States
Eszak-Kozep-budai Centrum, Uj Szent Janos Korhaz /ID# 236993
COMPLETED

Budapest, 1125, Hungary
Florida Research Center, Inc. /ID# 236514
RECRUITING

Miami, Florida, 33174, United States
Frederick County Pediatrics /ID# 234519
COMPLETED

New Market, Maryland, 21774-6154, United States
Global Research Associates /ID# 234646
RECRUITING

Atlanta, Georgia, 30315, United States
HELIOS Klinikum Wuppertal /ID# 237322
COMPLETED

Wuppertal, 42283, Germany
HealthStar Research of Hot Springs PLLC /ID# 234609
RECRUITING

Hot Springs, Arkansas, 71913, United States
Hospital Universitario Dr. Peset /ID# 236755
COMPLETED

Valencia, 46017, Spain
IPS Research Company /ID# 237672
COMPLETED

Oklahoma City, Oklahoma, 73106, United States
Indiana University Health Riley Hospital for Children /ID# 235400
COMPLETED

Indianapolis, Indiana, 46202, United States
Instytut Centrum Zdrowia Matki Polki /ID# 237438
COMPLETED

Lodz, Łódź Voivodeship, 93-338, Poland
Kindred Medical Institute, LLC /ID# 237368
COMPLETED

Corona, California, 92879, United States
Kings College Hospital NHS Foundation Trust /ID# 236305
COMPLETED

London, Greater London, SE5 9RS, United Kingdom
Korczowski Bartosz Gabinet Lekarski /ID# 234683
COMPLETED

Rzeszów, Podkarpackie Voivodeship, 35-302, Poland
MHATSv.Ivan Rilski /ID# 235399
COMPLETED

Kozloduy, 3320, Bulgaria
MNGI Digestive Health, P. A. /ID# 238057
COMPLETED

Minneapolis, Minnesota, 55413-2195, United States
Manitoba Institute of Child Health /ID# 235448
COMPLETED

Winnepeg, R3E 3P4, Canada
Medical center 1 Sevlievo /ID# 237473
COMPLETED

Sevlievo, Gabrovo, 5400, Bulgaria
Michael W. Simon, MD, PSC /ID# 236517
COMPLETED

Lexington, Kentucky, 40517, United States
Preferred Primary Care Physicians, Inc. /ID# 236436
RECRUITING

Pittsburgh, Pennsylvania, 15236, United States
Sleep Care Research Institute d/b/a Clinical Research Institute /ID# 236343
RECRUITING

Stockbridge, Georgia, 30281, United States
Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet /ID# 237341
COMPLETED

Sopron, 9400, Hungary
South Miami Medical & Research Group Inc. /ID# 234655
RECRUITING

Miami, Florida, 33155, United States
Specjalistyczne Gabinety Sp. z o.o. /ID# 236347
COMPLETED

Krakow, Lesser Poland Voivodeship, 30-539, Poland
Sun Research Institute /ID# 236933
COMPLETED

San Antonio, Texas, 78215, United States
Sunrise Research Institute /ID# 237382
COMPLETED

Miami, Florida, 33130, United States
Texas Children's Hospital /ID# 238304
RECRUITING

Houston, Texas, 77030-2608, United States
University Hospital Plovdiv /ID# 235450
COMPLETED

Plovdiv, 4001, Bulgaria
Valencia Medical & Research Center /ID# 234672
RECRUITING

Miami, Florida, 33165, United States
Vita Verum Medical Bt. /ID# 234321
COMPLETED

Székesfehérvár, 8000, Hungary
West Virginia University Hospitals /ID# 256841
RECRUITING

Morgantown, West Virginia, 26506, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.