Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a smarter pacemaker ease a common type of heart failure?

NCT ID NCT06678841

Recruiting now Disease control Sponsor: Medtronic Cardiac Rhythm and Heart Failure Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 29 times

Summary

This study tests whether a pacemaker programmed to each person's needs can improve heart failure symptoms and reduce hospital visits in people with a type of heart failure where the heart pumps normally but is too stiff (HFpEF). About 700 adults aged 40 and older with recent heart failure episodes or symptoms will receive either personalized pacing or minimal pacing. The goal is to see if this approach improves survival, quality of life, and exercise ability over 12 months.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner - University Medical Center Phoenix

    RECRUITING

    Phoenix, Arizona, 85006, United States

  • CHU Toulouse - Hôpital Rangueil

    RECRUITING

    Toulouse, 50032, France

  • Cardiovascular Institute of Northwest Florida

    RECRUITING

    Panama City, Florida, 32405, United States

  • Cardiovascular Institute of the South

    RECRUITING

    Houma, Louisiana, 70360, United States

  • Centre Hospitalier Universitaire Besancon - Hôpital Jean Minjoz

    RECRUITING

    Besançon, 25030, France

  • Centre Hospitalier Universitaire de Clermont-Ferrand - Gabriel-Montpied

    RECRUITING

    Clermont-Ferrand, 63003, France

  • Charleston Area Medical Center (CAMC) Memorial Hospital

    RECRUITING

    Charleston, West Virginia, 25304, United States

  • Dallas VA Medical Center

    RECRUITING

    Dallas, Texas, 75216, United States

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Fakultni nemocnice Královské Vinohrady

    RECRUITING

    Prague, 100 34, Czechia

  • Froedtert Hospital

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06106, United States

  • Hôpitaux Universitaires de Genève

    RECRUITING

    Geneva, 1205, Switzerland

  • Inova Fairfax Hospital

    RECRUITING

    Falls Church, Virginia, 22042, United States

  • Kokura Memorial Hospital

    RECRUITING

    Kitakyushu, Fukuoka, 802-8555, Japan

  • Lancaster General Hospital

    RECRUITING

    Lancaster, Pennsylvania, 17602, United States

  • Lankenau Institute for Medical Research

    RECRUITING

    Wynnewood, Pennsylvania, 19096, United States

  • M Health Fairview University of Minnesota Medical Center - East Bank

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • Manchester University NHS Foundation Trust - Manchester Royal Infirmary

    RECRUITING

    Manchester, M13 9WL, United Kingdom

  • Medical University of South Carolina (MUSC)

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Mount Carmel East

    RECRUITING

    Columbus, Ohio, 43219, United States

  • Norton Healthcare

    RECRUITING

    Louisville, Kentucky, 40295, United States

  • Ordensklinikum Linz GmbH / Elisabethinen

    RECRUITING

    Linz, 4010, Austria

  • Oslo Universitetssykehus-Rikshospitalet

    RECRUITING

    Oslo, 0372, Norway

  • Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong

  • Queen Elizabeth Hospital (Hong Kong)

    RECRUITING

    Hong Kong, Hong Kong

  • Saint Lukes Mid America Heart Institute

    RECRUITING

    Kansas City, Missouri, 64111, United States

  • Saint Pauls Hospital

    RECRUITING

    Vancouver, V6Z 1Y6, Canada

  • Saint Thomas Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Sarawak Heart Centre

    RECRUITING

    Kota Samarahan, 94300, Malaysia

  • Sutter Health Hospital

    RECRUITING

    San Francisco, California, 94107, United States

  • Texas Health Research & Education Institute

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • The Alfred Hospital

    RECRUITING

    Melbourne, Victoria, 3004, Australia

  • The Leeds Teaching Hospitals NHS Trust - Leeds General Infirmary

    RECRUITING

    Leeds, LS1 3EX, United Kingdom

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The Prince Charles Hospital

    RECRUITING

    Chermside, Queensland, 4032, Australia

  • The University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60637, United States

  • The University of Vermont Medical Center

    RECRUITING

    Burlington, Vermont, 05401, United States

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States

  • Universitair Ziekenhuis Antwerpen

    RECRUITING

    Edegem, 2650, Belgium

  • University Medical Centre Ljubljana

    RECRUITING

    Ljubljana, 1000, Slovenia

Conditions

Explore the condition pages connected to this study.

HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF