New blood filter could save lives in severe pancreatitis

NCT ID NCT07267169

Recruiting now Disease control Sponsor: Efferon JSC Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a device called Efferon LPS that filters toxins and inflammatory substances from the blood. It is being given to 150 people with severe acute pancreatitis within 24 hours of ICU admission. The goal is to see if it reduces organ failure and improves outcomes compared to standard therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Efferon LPS device (blood filter that removes toxins and inflammatory substances)
What this could lead to: If it works, this could provide a new way to reduce organ damage and improve survival in severe acute pancreatitis.
What could go wrong: This is an early-stage trial with no phase designation, so results are uncertain. The device is used alongside standard care, so its added benefit is not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute pancreatitis pancreatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATITIS, ACUTE

Contacts and locations

Locations

N.I. Pirogov City Clinical Hospital No. 1
RECRUITING

Moscow, Russia
N.V. Sklifosovsky Research Institute for Emergency Medicine
RECRUITING

Moscow, Russia
North-Western district scientific and clinical center named after L. G. Sokolov Federal Medical and Biological Agency
RECRUITING

Saint Petersburg, 194291, Russia
Perm regional clinical hospital
RECRUITING

Perm, 614045, Russia
Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
RECRUITING

Kazan', 420064, Russia
S.S. Yudin City Clinical Hospital
RECRUITING

Moscow, 115446, Russia
State Clinical Hospital "Regional Clinical Hospital No 2" of the Ministry of Healthcare of Krasnodar Territory
RECRUITING

Krasnodar, 350012, Russia
V.P. Demikhov City Clinical Hospital No. 68
RECRUITING

Moscow, 115280, Russia

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