New blood filter could save lives in severe pancreatitis

NCT ID NCT07267169

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a device called Efferon LPS that filters toxins and inflammatory substances from the blood. It is being given to 150 people with severe acute pancreatitis within 24 hours of ICU admission. The goal is to see if it reduces organ failure and improves outcomes compared to standard therapy alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Efferon LPS device (blood filter that removes toxins and inflammatory substances)

What this could lead to

If it works, this could provide a new way to reduce organ damage and improve survival in severe acute pancreatitis.

What could go wrong

This is an early-stage trial with no phase designation, so results are uncertain. The device is used alongside standard care, so its added benefit is not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute pancreatitis pancreatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • N.I. Pirogov City Clinical Hospital No. 1

    RECRUITING

    Moscow, Russia

    Contact Email: •••••@•••••

  • N.V. Sklifosovsky Research Institute for Emergency Medicine

    RECRUITING

    Moscow, Russia

    Contact Email: •••••@•••••

  • North-Western district scientific and clinical center named after L. G. Sokolov Federal Medical and Biological Agency

    RECRUITING

    Saint Petersburg, 194291, Russia

    Contact Email: •••••@•••••

  • Perm regional clinical hospital

    RECRUITING

    Perm, 614045, Russia

    Contact Email: •••••@•••••

  • Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan

    RECRUITING

    Kazan', 420064, Russia

    Contact Email: •••••@•••••

  • S.S. Yudin City Clinical Hospital

    RECRUITING

    Moscow, 115446, Russia

    Contact Email: •••••@•••••

  • State Clinical Hospital "Regional Clinical Hospital No 2" of the Ministry of Healthcare of Krasnodar Territory

    RECRUITING

    Krasnodar, 350012, Russia

    Contact Email: •••••@•••••

  • V.P. Demikhov City Clinical Hospital No. 68

    RECRUITING

    Moscow, 115280, Russia

    Contact Email: •••••@•••••