PANCREATITIS, ACUTE

This study tests a device called Efferon LPS that filters toxins and inflammatory substances from the blood. It is being given to 150 people with severe acute pancreatitis within 24 hours of ICU admission. The goal is to see if it reduces organ failure and improves outcomes compa…

This study tests two diabetes medications, pioglitazone and empagliflozin, to see which one better controls blood sugar in people whose diabetes is caused by chronic or recurrent acute pancreatitis. About 40 adults aged 18-80 with this type of diabetes will take one of the drugs,…

This study tests whether a short course of the steroid hydrocortisone can reduce inflammation and improve outcomes for people with severe pancreatitis. Researchers will give the drug or a placebo to 86 ICU patients and track their organ failure scores and hospital stay length. Th…

This study tests whether giving extra IV fluids along with a standard anti-inflammatory suppository can better prevent pancreatitis after a procedure to break up pancreatic stones. About 1250 adults with chronic pancreatitis will be randomly assigned to receive either the combina…

This study tests whether increasing the dose of varenicline or adding bupropion helps people with recurrent acute or chronic pancreatitis quit smoking. All 45 participants start with standard varenicline; those still smoking after 6 weeks are randomly assigned to a higher dose, a…

This observational study will monitor 1,000 patients in Slovakia and Czechia who undergo ERCP, a procedure to treat bile duct problems. The main goal is to track how often pancreatitis occurs after the procedure and whether hospitals are following recommended prevention steps. Th…

This study follows 150 patients who have had part of their pancreas removed. Researchers will measure blood levels of amylase and lipase before, during, and after surgery to see if high levels can predict serious complications like pancreatitis. The goal is to improve how doctors…

This study tracks 300 adults in Tehran who are getting a pancreas biopsy (EUS-guided FNB) to see how often pancreatitis occurs afterward. Researchers will measure enzyme levels 24 hours later and check for pain. The goal is to find out which factors—like age, gender, or biopsy lo…