PANCREATITIS, ACUTE

This study tests two common diabetes drugs, pioglitazone and empagliflozin, to see which one better controls blood sugar in people whose diabetes is caused by chronic or recurrent acute pancreatitis. About 40 adults aged 18 to 80 will take one of the two medications, and research…

This study tests a device called Efferon LPS that filters harmful substances from the blood of people with severe acute pancreatitis. The goal is to see if adding this filter to standard care reduces organ failure and improves survival. About 150 adults with moderate to severe pa…

This study tests whether giving a short course of intravenous hydrocortisone, an anti-inflammatory steroid, to adults with severe acute pancreatitis can reduce inflammation and improve recovery. About 86 participants in intensive care will receive either the drug or a placebo. Th…

This study looks at whether increasing the dose of a stop-smoking medication or adding another drug helps people with pancreatitis quit smoking. All 45 participants start with the standard dose of varenicline. If they still smoke after 6 weeks, they are randomly assigned to a hig…

This study tests whether giving extra fluids through a vein along with a standard anti-inflammatory drug (indometacin) can better prevent pancreatitis after a procedure that uses shock waves to break up pancreatic stones. About 1,250 adults with painful chronic pancreatitis will …

This study looks at 150 adults having pancreas surgery to understand why some develop high blood levels of amylase, a sign of pancreas irritation. The goal is to better predict and manage complications after surgery. Researchers will track lab results and outcomes to improve defi…

This study aims to find out how often people develop pancreatitis (inflammation of the pancreas) after a special biopsy called EUS-guided fine needle biopsy. Researchers will follow 300 adults who need this biopsy and check for pancreatitis 24 hours later. The goal is to identify…

This study will watch 1,000 adults in Slovakia and Czechia who are getting an ERCP, a procedure to fix bile duct or pancreas problems. The goal is to see how often pancreatitis develops afterward and whether hospitals are following recommended prevention steps. The results will h…