Brainwave training tested for aphasia recovery

NCT ID NCT04290988

Terminated Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether EEG neurofeedback—a type of brain training that uses real-time brainwave readings—can help people with aphasia (trouble speaking or understanding language) improve their communication, sleep, and anxiety. Seven adults with aphasia from stroke or primary progressive aphasia took part. Each person received both real and sham (fake) neurofeedback sessions in a crossover design to see if the real training made a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: EEG neurofeedback (device-based brain training)
What this could lead to: If it works, this could point toward a non-invasive way to improve language and quality of life for people with aphasia.
What could go wrong: This was a very small, early-stage trial (only 7 participants) that was terminated, so results are limited. The sham-controlled design helps, but the tiny sample means findings may not be reliable or generalizable.

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Conditions

The condition(s) this trial relates to.

anxiety disorder aphasia Communication Language primary progressive aphasia Speech stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APHASIA PRIMARY PROGRESSIVE APHASIA STROKE

Contacts and locations

Locations

Johns Hopkins School of Medicine

Baltimore, Maryland, 21287, United States

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