Teens to get Weight-Loss drug right after surgery in new trial

NCT ID NCT06934655

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether restarting semaglutide (Wegovy) just two weeks after sleeve gastrectomy helps teens with severe obesity lose more weight than surgery alone. About 150 teens aged 12–18 who were already on semaglutide before surgery will be randomly assigned to restart the drug or receive standard care for 24 months. Researchers will track weight, blood sugar, and eating behaviors to see if early re-initiation is safe and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Semaglutide (Wegovy) injection

What this could lead to

If it works, this could show that restarting semaglutide soon after weight-loss surgery helps teens lose more weight and improve their health long-term.

What could go wrong

This is a single-center trial with 150 participants, so results may not apply to all teens. Side effects like nausea or vomiting are common with semaglutide, and the study is not yet recruiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

morbid obesity obesity disorder Pediatric Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027, United States