A simple blood test may catch hidden heart failure before It's too late
NCT ID NCT07731490
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
Heart failure often goes undiagnosed because its early symptoms—like fatigue and shortness of breath—are mistaken for normal aging. This study tests whether a three-part strategy can change that: raising awareness among patients and doctors, using a blood test (NT-proBNP) to spot heart failure early in high-risk older adults, and starting guideline-recommended treatment right away. Researchers will track whether this approach reduces hospitalizations for acute heart failure over 18 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a strategy combining increased awareness, NT-proBNP blood testing, and guideline-directed heart failure treatment
- What this could lead to
- If successful, this approach could become a standard way to catch heart failure early and prevent hospitalizations in older adults.
- What could go wrong
- The trial is large but observational, so it cannot prove cause and effect. The strategy may not reduce hospitalizations as hoped.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cantonal Hospital Baden
NOT_YET_RECRUITINGBaden, 5404, Switzerland
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Erasmus MC Rotterdam
NOT_YET_RECRUITINGRotterdam, 3015, Netherlands
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Herzzentrum Leipzig, Klinik für Innere Medizin/Kardiologie
NOT_YET_RECRUITINGLeipzig, 04289, Germany
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Hospital Istituto Cardiocentro Ticino
NOT_YET_RECRUITINGLugano, 6900, Switzerland
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KSA Kantonsspital Aarau
NOT_YET_RECRUITINGAarau, 5001, Switzerland
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Kantonsspital Luzern
NOT_YET_RECRUITINGLucerne, 6000, Switzerland
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Kantonsspital St. Gallen
NOT_YET_RECRUITINGSankt Gallen, 9007, Switzerland
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Konkuk University Medical Center
RECRUITINGSeoul, South Korea
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Queen Giovanna University Hospital
NOT_YET_RECRUITINGSofia, 1527, Bulgaria
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Royal Infirmary Edinburgh
NOT_YET_RECRUITINGEdinburgh, EH16 4SB, United Kingdom
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St. Claraspital AG
NOT_YET_RECRUITINGBasel, 4058, Switzerland
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Stadtspital Zürich
NOT_YET_RECRUITINGZurich, 8063, Switzerland
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University Hospital Basel
RECRUITINGBasel, Basel, 4031, Switzerland
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University Hospital Freiburg-Bad Krozingen
NOT_YET_RECRUITINGFreiburg im Breisgau, 79106, Germany
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University Hospital Genève
NOT_YET_RECRUITINGGeneva, 1205, Switzerland
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University Hospital Lausanne
NOT_YET_RECRUITINGLausanne, Lausanne, 1005, Switzerland
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University Hospital Pisa
NOT_YET_RECRUITINGPisa, 56126, Italy
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University Hospital Ramón y Cajal Madrid
NOT_YET_RECRUITINGMadrid, 28034, Spain
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University Hospital Zurich
NOT_YET_RECRUITINGZurich, 8091, Switzerland
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Universitätsklinik für Innere Medizin II
NOT_YET_RECRUITINGVienna, 1090, Austria
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Universitätsklinikum der Ruhr-Universität Bochum
NOT_YET_RECRUITINGHerne, 44625, Germany
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Other studies related to the condition(s) this trial covers.
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