Heart failure patients could go home sooner with injectable diuretic

NCT ID NCT07018297

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether people hospitalized for acute heart failure can be discharged early and continue treatment at home using a subcutaneous injection of furosemide (a diuretic) instead of staying in the hospital for standard IV diuretics. About 250 adults will be randomly assigned to either early discharge with the injection or standard care. The main goal is to see if the early discharge approach is no worse than standard care in terms of days alive and out of the hospital after 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
subcutaneous furosemide (Lasix ONYU)
What this could lead to
If it works, this could allow some heart failure patients to go home earlier and continue treatment there, reducing hospital stays without increasing risks.
What could go wrong
This is a relatively small trial (250 people) and only tests non-inferiority, not superiority. The approach may not work for all patients, and there is a risk of complications from self-administered injections at home.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor Scott and White Health System

    Dallas, Texas, 75246, United States

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75209, United States

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