New combo therapy shows promise for advanced bladder cancer

NCT ID NCT05137262

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 27 times

Summary

This study tests whether adding the immunotherapy drug durvalumab to standard chemotherapy helps people with bladder cancer that has spread to nearby lymph nodes. About 60 participants will receive either chemo alone or chemo plus durvalumab, followed by maintenance durvalumab for up to a year. The main goal is to see if the combination leads to a higher rate of complete tumor disappearance before surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Indiana University

    Bloomington, Indiana, 47405, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.