Could two blood thinners save more hearts after bypass?

NCT ID NCT03560310

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares two blood thinners (ticagrelor plus aspirin) against aspirin alone after coronary artery bypass grafting (CABG) in people who recently had a heart attack or unstable angina. Over 2,200 participants are being followed for 12 months to see if the dual therapy reduces major heart problems like death, heart attack, or stroke. The goal is to find the best way to protect patients after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ticagrelor and aspirin (acetylsalicylic acid)

What this could lead to

If it works, this could lead to a better standard treatment after heart bypass surgery to prevent future heart attacks, strokes, or death.

What could go wrong

This is a late-stage trial, but adding a second blood thinner increases bleeding risk. The benefit may be small or not outweigh the risks for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aalborg University Hospital

    Aalborg, Denmark

  • Aarhus University Hospital

    Aarhus, Denmark

  • Blekinge Hospital

    Karlskrona, Sweden

  • Haukeland University Hospital

    Trondheim, Norway

  • Helsinki University Hospital

    Helsinki, Finland

  • Karolinska University Hospital

    Stockholm, Sweden

  • Kuopio University Hospital

    Kuopio, Finland

  • Landspítali University Hospital

    Reykjavik, Iceland

  • Linköping University Hospital

    Linköping, Sweden

  • Odense University Hospital

    Odense, Denmark

  • Oslo University Hospital

    Oslo, Norway

  • Oulu University Hospital

    Oulu, Finland

  • Rigshospitalet

    Copenhagen, Denmark

  • Sahlgrenska University Hospital

    Gothenburg, Sweden

  • Skåne University Hospital

    Lund, Sweden

  • St. Olavs hospital, University Hospital

    Bergen, Norway

  • Tampere University Hospital

    Tampere, Finland

  • Turku University Hospital

    Turku, Finland

  • University Hospital of North Norway

    Tromsø, Norway

  • University Hospital of Umeå

    Umeå, Sweden

  • Uppsala University Hospital

    Uppsala, Sweden

  • Örebro University Hospital

    Örebro, Sweden