Could two blood thinners save more hearts after bypass?

NCT ID NCT03560310

Ongoing Disease control Sponsor: Vastra Gotaland Region Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares two blood thinners (ticagrelor plus aspirin) against aspirin alone after coronary artery bypass grafting (CABG) in people who recently had a heart attack or unstable angina. Over 2,200 participants are being followed for 12 months to see if the dual therapy reduces major heart problems like death, heart attack, or stroke. The goal is to find the best way to protect patients after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ticagrelor and aspirin (acetylsalicylic acid)
What this could lead to: If it works, this could lead to a better standard treatment after heart bypass surgery to prevent future heart attacks, strokes, or death.
What could go wrong: This is a late-stage trial, but adding a second blood thinner increases bleeding risk. The benefit may be small or not outweigh the risks for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CORONARY SYNDROME

Contacts and locations

Locations

Aalborg University Hospital

Aalborg, Denmark
Aarhus University Hospital

Aarhus, Denmark
Blekinge Hospital

Karlskrona, Sweden
Haukeland University Hospital

Trondheim, Norway
Helsinki University Hospital

Helsinki, Finland
Karolinska University Hospital

Stockholm, Sweden
Kuopio University Hospital

Kuopio, Finland
Landspítali University Hospital

Reykjavik, Iceland
Linköping University Hospital

Linköping, Sweden
Odense University Hospital

Odense, Denmark
Oslo University Hospital

Oslo, Norway
Oulu University Hospital

Oulu, Finland
Rigshospitalet

Copenhagen, Denmark
Sahlgrenska University Hospital

Gothenburg, Sweden
Skåne University Hospital

Lund, Sweden
St. Olavs hospital, University Hospital

Bergen, Norway
Tampere University Hospital

Tampere, Finland
Turku University Hospital

Turku, Finland
University Hospital of North Norway

Tromsø, Norway
University Hospital of Umeå

Umeå, Sweden
Uppsala University Hospital

Uppsala, Sweden
Örebro University Hospital

Örebro, Sweden

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