Can tuning brain stimulation at night help Parkinson's patients sleep better?

NCT ID NCT07110376

Recruiting now Symptom relief Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether changing the strength of deep brain stimulation (DBS) during sleep can help people with Parkinson's disease sleep better. Ten participants will try three different nighttime DBS settings (off, half strength, and full strength) for two weeks each. The goal is to see which setting improves sleep efficiency the most, using a headband to track sleep and brain recordings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Deep brain stimulation (DBS) with varying nighttime amplitude settings (0%, 50%, 100% of clinical settings)
What this could lead to: If successful, this could point toward a way to adjust DBS during sleep to improve rest and quality of life for people with Parkinson's.
What could go wrong: This is a very small, early exploratory study with only 10 participants, so results may not apply to everyone. It focuses on sleep, not on changing the course of Parkinson's itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

Cleveland Clinic
RECRUITING

Cleveland, Ohio, 441950001, United States

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