Scientists hunt for biomarkers to unlock DM1 treatments

NCT ID NCT07700225

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study follows 1,000 adults with myotonic dystrophy type 1 (DM1) over time to measure how the disease progresses. Researchers will track walking speed, hand muscle relaxation, grip strength, heart and lung function, and daily activity. The goal is to establish reliable biomarkers and clinical endpoints that can be used in future trials to test potential treatments for this progressive, multi-system disorder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could identify reliable biomarkers and clinical endpoints that speed up development of treatments for myotonic dystrophy type 1.
What could go wrong
This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results depend on long-term participant follow-up.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Virginia Commonwealth University

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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