Can watching the course of myotonic dystrophy unlock better care?

NCT ID NCT07732439

Not yet recruiting Knowledge-focused Sponsor: Lupin Ltd. Source: ClinicalTrials.gov ↗

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This study follows 100 adults with myotonic dystrophy (types 1 or 2) for two years to understand how muscle stiffness, daily function, and heart health change over time. Researchers will look back at up to 18 months of past medical records and then track participants with clinic visits at the start, 12 months, and 24 months. The goal is to map the natural course of the disease and identify which symptoms most affect quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better predict how myotonic dystrophy progresses and identify which symptoms matter most to patients.
What could go wrong
This is an observational study, not a treatment trial, so it will not test any new therapy. The small number of participants (100) may limit how broadly the findings apply.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU LA TIMONE - Service des Maladies

    Marseille, 13005, France

  • CHU de Lille - Hôpital

    Lille, 59037, France

  • CHU de Toulouse - Hôpital

    Toulouse, 40031, France

  • Centre de référence des maladies neuromusculaires

    Nantes, 44093, France

  • Centre hospitalier Universitaire d'Angers

    Angers, 75651, France

  • Hôpital Pitié Salpêtrière

    Paris, 75013, France

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