MYOTONIC DYSTROPHY TYPE 1 (DM1)
Clinical trials for MYOTONIC DYSTROPHY TYPE 1 (DM1) explained in plain language.
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New drug trial aims to ease muscle symptoms in myotonic dystrophy
Disease control Recruiting nowThis study tests a new medicine, DYNE-101, in 150 adults with myotonic dystrophy type 1, a condition that causes muscle weakness and stiffness. Participants will receive either the drug or a placebo for 48 weeks to see if it improves muscle function and daily activities. The goal…
Matched conditions: MYOTONIC DYSTROPHY TYPE 1 (DM1)
Phase: PHASE3 • Sponsor: Dyne Therapeutics • Aim: Disease control
Last updated May 17, 2026 07:00 UTC
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New drug DYNE-101 aims to ease muscle stiffness in rare disease
Disease control Recruiting nowThis study tests a new medicine called DYNE-101 for people with myotonic dystrophy type 1, a condition that causes muscle weakness and stiffness. The trial will check if the drug is safe and helps reduce muscle symptoms. About 116 adults will receive either DYNE-101 or a placebo …
Matched conditions: MYOTONIC DYSTROPHY TYPE 1 (DM1)
Phase: PHASE1, PHASE2 • Sponsor: Dyne Therapeutics • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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New drug VX-670 enters human testing for muscle disease DM1
Disease control Recruiting nowThis early-stage trial tests the safety and tolerability of a new drug, VX-670, in 44 adults with myotonic dystrophy type 1 (DM1). Participants receive either the drug or a placebo in single or multiple doses. The study aims to find the right dose and understand how the drug move…
Matched conditions: MYOTONIC DYSTROPHY TYPE 1 (DM1)
Phase: PHASE1, PHASE2 • Sponsor: Vertex Pharmaceuticals Incorporated • Aim: Disease control
Last updated Apr 30, 2026 15:49 UTC
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Music sessions tested as therapy for rare muscle disease in kids
Symptom relief Recruiting nowThis study explores whether weekly music and movement sessions are practical and enjoyable for children aged 6 to 18 with myotonic dystrophy type 1 (DM1). Over 10 weeks, participants attend 45-minute music classes, undergo physical and cognitive tests, and provide biological samp…
Matched conditions: MYOTONIC DYSTROPHY TYPE 1 (DM1)
Phase: NA • Sponsor: Hanns Lochmuller • Aim: Symptom relief
Last updated May 17, 2026 06:52 UTC
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Can a home kit unlock the secrets of a mysterious muscle disease?
Knowledge-focused Recruiting nowThis study aims to understand why myotonic dystrophy type 1 affects people so differently. Researchers will have 1,000 adults with DM1 do simple tests at home, like grip strength and memory games, and provide a blood sample for genetic analysis. The goal is to find better ways to…
Matched conditions: MYOTONIC DYSTROPHY TYPE 1 (DM1)
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC