New hope for muscle disease: experimental drug VX-670 enters human trials
NCT ID NCT06185764
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests the safety and tolerability of a new drug called VX-670 in 52 adults with myotonic dystrophy type 1 (DM1), a genetic condition that causes muscle weakness and other problems. Participants receive either VX-670 or a placebo, and researchers will monitor side effects and how the drug moves through the body. The goal is to find a safe dose for future studies, not to cure the disease.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Altasciences Montreal
RECRUITINGMontreal, Canada
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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CHU Research Centre of Quebec
RECRUITINGQuébec, Canada
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Centro Clinico NeMO
RECRUITINGMilan, Italy
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Clinical Research Facility, Queen Elizabeth University Hospital
RECRUITINGGlasgow, United Kingdom
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Hopital de Chicoutimi
RECRUITINGChicoutimi, Canada
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Hospital Universitario y Politécnico La Fe
RECRUITINGValencia, Spain
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Leonard Wolfson Experimental Neurology Centre CRF
RECRUITINGLondon, United Kingdom
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Ludwig Maximilians Universitaet Muenchen
RECRUITINGMünchen, Germany
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Maastricht University Medical Center
RECRUITINGMaastricht, Netherlands
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McGIll University
RECRUITINGMontreal, Canada
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Neuromuscular Reference Center Institute of Myology
RECRUITINGParis, France
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Neuroscience Clinical Trials Unit, Alfred Brain
RECRUITINGMelbourne, Australia
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Royal Hallamshire Hospital
RECRUITINGSheffield, United Kingdom
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Salford Royal Hospital
RECRUITINGSalford, United Kingdom
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St. George's University Hospital
RECRUITINGLondon, United Kingdom
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Stanford Neuromuscular Research
RECRUITINGSan Carlos, California, 94070, United States
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Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg
RECRUITINGLeuven, Belgium
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University of Florida Clinical Research Center
RECRUITINGGainesville, Florida, 32608, United States
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University of Kansas Medical Center
RECRUITINGFairway, Kansas, 66205, United States
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University of Ottawa
RECRUITINGOttawa, Canada
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Virginia Commonwealth University (Sanger Hall)
RECRUITINGRichmond, Virginia, 23298, United States
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Wake Forest Baptist Health
RECRUITINGWinston-Salem, North Carolina, 27104, United States
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Washington University School of Medicine / St. Louis Children's Hospital
RECRUITINGSt Louis, Missouri, 63110, United States
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Wesley Research Institute
RECRUITINGAuchenflower, Australia