DM1
Clinical trials for DM1 explained in plain language.
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New drug DYNE-101 aims to ease muscle symptoms in DM1
Disease control Recruiting nowThis Phase 3 trial tests whether DYNE-101 can improve muscle function and daily life in 150 adults with myotonic dystrophy type 1 (DM1). Participants receive either the drug or a placebo by IV every few weeks for 48 weeks. The study measures how quickly people can stand from a ch…
Matched conditions: DM1
Phase: PHASE3 • Sponsor: Dyne Therapeutics • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Scientists hunt for biomarkers to unlock DM1 treatments
Knowledge-focused Recruiting nowThis study follows 1,000 adults with myotonic dystrophy type 1 (DM1) over time to measure how the disease progresses. Researchers will track walking speed, hand muscle relaxation, grip strength, heart and lung function, and daily activity. The goal is to establish reliable biomar…
Matched conditions: DM1
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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700-Patient study seeks key clues to muscle disease
Knowledge-focused Recruiting nowThis study is following 700 adults with myotonic dystrophy type 1 (DM1) over two years. Researchers are measuring walking speed, lung function, and muscle tissue changes to find reliable markers of disease progression. The goal is to improve future clinical trials by better under…
Matched conditions: DM1
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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No travel needed: largest Home-Based study of myotonic dystrophy launches
Knowledge-focused Recruiting nowThis study aims to understand why myotonic dystrophy type 1 affects people so differently. Researchers will remotely assess muscle strength, memory, and activity in 1,000 participants, and analyze their DNA from a blood sample. All activities are done from home using a mailed too…
Matched conditions: DM1
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Spanish researchers launch massive DM1 registry to unlock disease secrets
Knowledge-focused Recruiting nowThis study aims to create a national registry for people with Myotonic Dystrophy Type 1 (DM1) in Spain. Researchers will collect clinical data, genetic information, and patient reports from up to 3,000 participants. The goal is to better understand the disease and identify people…
Matched conditions: DM1
Sponsor: Fundació Institut Germans Trias i Pujol • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC