Can a common acidifier restore water pill power in heart failure?

NCT ID NCT06209359

First seen May 24, 2026 · Last updated Jun 13, 2026 · Updated 5 times

Summary

This study looks at why some people with heart failure become resistant to diuretics (water pills). Researchers will test whether a medication called ammonium chloride can help the kidneys remove more sodium. 50 adults with heart failure and diuretic resistance will take either the study drug or a placebo in a crossover design. The goal is to understand the body's response, not to provide a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.