One size Doesn't fit all: new trial tailors blood thinners after joint surgery

NCT ID NCT06581965

First seen Sep 30, 2025 · Last updated Apr 29, 2026 · Updated 30 times

Summary

This study is testing whether giving different amounts of blood thinners based on a person's risk can prevent dangerous blood clots and reduce bleeding after hip or knee replacement. About 10,000 adults having elective hip or knee replacement will be assigned to either standard treatment or a personalized plan (shorter for low-risk, stronger and longer for high-risk). The goal is to see if this tailored approach works better than the current one-size-fits-all method.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alrijne

    RECRUITING

    Leiderdorp, South Holland, 2353 GA, Netherlands

  • Anna Ziekenhuis

    RECRUITING

    Geldrop, North Brabant, 5564EH, Netherlands

  • Bergman Clinics

    RECRUITING

    Naarden, North Holland, 1411DE, Netherlands

  • Bravis ziekenhuis

    NOT_YET_RECRUITING

    Roosendaal, North Brabant, 4708 AE, Netherlands

  • Elisabeth-TweeSteden Ziekenhuis

    RECRUITING

    Tilburg, North Brabant, 5022GC, Netherlands

  • Gelre Ziekenhuizen

    RECRUITING

    Apeldoorn, Gelderland, 7334 DZ, Netherlands

  • Isala ziekenhuis

    RECRUITING

    Zwolle, Overijssel, 8025AB, Netherlands

  • OLVG

    RECRUITING

    Amsterdam, North Holland, 1091AC, Netherlands

  • Reinier Haga Orthopedisch Centrum

    RECRUITING

    Zoetermeer, South Holland, 2725NA, Netherlands

  • Zuyderland

    RECRUITING

    Geleen, Limburg, 6162 BG, Netherlands

Conditions

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