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New hope for teens on dialysis: drug targets severe itching

NCT ID NCT06593392

Recruiting now Symptom relief Sponsor: Vifor Fresenius Medical Care Renal Pharma Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a medicine called difelikefalin in teenagers aged 12 to 17 who are on hemodialysis and have moderate to severe itching. The goal is to see if the drug is safe and how much gets into the blood. About 18 teens will receive the medicine up to 4 times a week for 12 weeks during their regular dialysis visits.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome Pruritus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASES PRURITUS

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Alder Hey Childrens Hospital

    RECRUITING

    Liverpool, L14 5AB, United Kingdom

  • Guangzhou Women and Children's Medical Center

    RECRUITING

    Guangzhou, 510600, China

  • Hospital Sant Joan de Déu

    RECRUITING

    Barcelona, " 08950", Spain

  • Hospital Universitario Valle de Hebron

    RECRUITING

    Barcelona, 8035, Spain

  • Huazhong University of Science and Technology-Tongji Medical College-The Central Hospital of Wuhan

    RECRUITING

    Wuhan, 430032, China

  • Jalila Children's Specialty Hospital

    RECRUITING

    Dubai, 25314, United Arab Emirates

  • King Abdullah Specialized Children's Hospital (KASCH)

    RECRUITING

    Riyadh, 14611, Saudi Arabia

  • King Faisal Specialist Hospital and Research Center, Riyadh

    RECRUITING

    Riyadh, 11564, Saudi Arabia

  • Pan and Aglaia Kyriakou Children's Hospital

    RECRUITING

    Athens, 11527, Greece

  • Royal Hospital for Children Glasgow

    RECRUITING

    Glasgow, G51 4TF, United Kingdom

  • Schneider Children's Medical Center of Israel

    RECRUITING

    Petah Tikva, 49202, Israel

  • Shaare Zedek Medical Center

    RECRUITING

    Jerusalem, 9103102, Israel

  • Sichuan University-West China Second University Hospital

    RECRUITING

    Chengdu, 610066, China

  • The Children's Hospital Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, 310003, China

  • The Children's Hospital of Fudan University

    RECRUITING

    Shanghai, 201102, China

  • The First Affiliated Hospital, Sun Yat-sen University

    RECRUITING

    Guangzhou, 510080, China

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