New program aims to cut unnecessary antibiotics in ventilated kids
NCT ID NCT04987840
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a diagnostic stewardship program—a set of guidelines to help doctors decide when to order respiratory cultures—can safely reduce antibiotic use in critically ill children on ventilators. Researchers will track changes in how often cultures are taken and how many antibiotics are prescribed across 15 children's hospitals. The goal is to find a way to lower antibiotic overuse without harming patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could provide hospitals with a proven strategy to reduce unnecessary antibiotic use in children on ventilators, lowering the risk of antibiotic resistance.
What could go wrong
This is a very small, early-stage implementation study with only 15 hospitals. It focuses on changing doctor behavior, not testing a new drug, so results may not apply broadly or lead to immediate patient benefits.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Hospital and Medical Center Omaha
Omaha, Nebraska, 68114, United States
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Children's Minnesota Hospital
Minneapolis, Minnesota, 55404, United States
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Cleveland Clinic Children's Hospital
Cleveland, Ohio, 44106, United States
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Dell Children's Medical Center
Austin, Texas, 78723, United States
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Johns Hopkins Children's Center
Baltimore, Maryland, 21287, United States
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Le Bonheur Children's Hospital
Memphis, Tennessee, 38103, United States
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Monroe Carell Jr. Children's Hospital
Nashville, Tennessee, 37232, United States