Can a simple inhaled antibiotic stop deadly pneumonia in ventilator patients?
NCT ID NCT07665788
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a 5-day course of inhaled amikacin can prevent ventilator-associated pneumonia in critically ill patients who already have a milder airway infection called tracheobronchitis. 250 adults on breathing machines will receive either the drug or a placebo. The goal is to see if the treatment reduces the chance of the infection spreading to the lungs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
inhaled amikacin
What this could lead to
If it works, this could offer a way to prevent a serious lung infection in critically ill patients on breathing machines.
What could go wrong
This is an early-stage trial with only 250 participants, so results may not apply to all patients. The treatment may not prevent pneumonia and could have side effects like kidney issues or hearing loss.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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01 - ORLEANS - Intensive care, University Hospital
Orléans, 45000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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02 - TOURS - Intensive care, University Hospital
Tours, 37044, France
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03 - STRASBOURG - Intensive care, University Hospital
Strasbourg, 67091, France
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04 - ARGENTEUIL - Intensive care, University Hospital
Argenteuil, France
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05 - LE MANS - Intensive care, University Hospital
Le Mans, 72037, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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06 - ANGERS - Intensive care, University Hospital
Angers, 49933, France
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07 - DIEPPE - Intensive care, University Hospital
Dieppe, 76202, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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08 - DIJON - Intensive care, University Hospital
Dijon, 21000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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09 - BOURG-EN-BRESSE, Intensive care, Hospital
Bourg-en-Bresse, 01012, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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10 - HENRI MONDOR, Intensive care, University Hospital
Créteil, 94010, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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11 - BLOIS, Intensive care, Hospital
Blois, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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12 - DREUX, Intensive care, Hospital
Dreux, 28100, France
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13 - BICHAT, Intensive care, Univerity Hospital
Paris, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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14 - VERSAILLES, Intensive care, Hospital
Le Chesnay, 78150, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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15 - LYON EH, Intensive care, University Hospital
Lyon, 69437, France
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16 - LYON SUD, Intensive care, University Hospital
Pierre-Bénite, 69495, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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17 - LOUIS MOURIER, Intensive care, University Hospital
Paris, 32700, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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