New drug hope for rare skin blister condition

NCT ID NCT05710185

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 15 times

Summary

This study tested a daily pill called deucravacitinib for people with palmoplantar pustulosis, a condition that causes painful, pus-filled blisters on the palms and soles. Only 3 adults with moderate-to-severe symptoms took the drug for 24 weeks. The goal was to see if it improved skin severity and quality of life. The study was terminated early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.