Brain zaps for better sleep? small trial tests DBS for Parkinson's insomnia

NCT ID NCT04116996

Recruiting now Symptom relief Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether turning on an extra deep brain stimulation (DBS) electrode in a brain region called the globus pallidus externa (GPe) can help people with Parkinson's disease who have severe insomnia. Ten participants aged 40-80 will report changes in their sleep quality using questionnaires. The goal is to see if this targeted stimulation can ease a common and troubling symptom.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (DBS) device
What this could lead to: If it works, this could offer a new way to improve sleep for people with Parkinson's disease who have severe insomnia.
What could go wrong: This is a very small, early study with only 10 participants, so results may not apply to everyone. The procedure involves brain surgery, which carries risks like infection or bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224, United States

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