Could an Anti-Inflammatory pill help control diabetes?

NCT ID NCT06047262

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This Phase 2 trial tests dapansutrile, an oral drug that reduces inflammation, in 300 adults with type 2 diabetes. The goal is to see if it improves blood sugar control and lowers the risk of diabetes-related complications. Participants are randomly assigned to receive either the drug or a placebo for comparison.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dapansutrile (an oral anti-inflammatory drug)

What this could lead to

If successful, this could offer a new way to manage type 2 diabetes by reducing inflammation, potentially lowering blood sugar and risk of complications.

What could go wrong

This is an early Phase 2 trial with 300 people, so results are not yet proven. The drug may not improve blood sugar control or could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Liege

    RECRUITING

    Liège, 4000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Deutsches Zentrum für Diabetesforschung Düsseldorf

    RECRUITING

    Düsseldorf, Nordrhein-Westphalen, 40225, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital Bichat

    RECRUITING

    Paris, Île-de-France Region, 75018, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopital Lariboisiere

    RECRUITING

    Paris, Île-de-France Region, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kantonsspital Olten

    RECRUITING

    Olten, Canton of Solothurn, 4600, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Basel

    TERMINATED

    Basel, Basel, 4031, Switzerland