New study tracks how common heart drug affects kidneys in transplant candidates

NCT ID NCT06868797

Recruiting now Knowledge-focused Sponsor: Central Hospital, Nancy, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study follows 103 advanced heart failure patients on a transplant waiting list to see how dapagliflozin affects the link between heart and kidney health. Researchers will measure a protein called suPAR in the blood over 6 months to track kidney damage. The goal is to better understand how heart failure and kidney function interact in these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dapagliflozin
What this could lead to: If successful, this could help doctors better understand and manage heart-kidney interactions in advanced heart failure patients.
What could go wrong: This is an observational study, not a treatment trial, so it won't prove dapagliflozin's effectiveness. Results may not apply to all heart failure patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

advanced heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Aphp Hegp
NOT_YET_RECRUITING

Paris, 75015, France
CHU Bordeaux
NOT_YET_RECRUITING

Pessac, 33600, France
CHU Grenoble
NOT_YET_RECRUITING

La Tronche, 38700, France
CHU Montpellier
NOT_YET_RECRUITING

Montpellier, 34295, France
CHU Rennes
NOT_YET_RECRUITING

Rennes, 35033, France
CHU Strasbourg
NOT_YET_RECRUITING

Strasbourg, 67091, France
CHU de Toulouse
NOT_YET_RECRUITING

Toulouse, 31059, France
Chru Nancy
RECRUITING

Vandœuvre-lès-Nancy, 54500, France
Chu Nantes
NOT_YET_RECRUITING

Nantes, 44093, France
Chu Rouen
NOT_YET_RECRUITING

Rouen, 76031, France
Hospice Civil de Lyon - Hôpital Louis PRADEL
NOT_YET_RECRUITING

Bron, 69500, France

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