Wound dressings that trap microbes: scientists test a Drug-Free approach
NCT ID NCT05089890
First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time
Summary
Researchers are investigating whether wound dressings coated with dialkylcarbamoyl chloride (DACC) can bind bacteria and fungi from hard-to-heal wounds. The study enrolls 30 adults with wounds such as diabetic foot ulcers, venous leg ulcers, pressure ulcers, or arterial leg ulcers that have not healed for at least six weeks. Participants use one of three DACC-coated dressings, and researchers measure the microbes attached to the dressing after two days using genetic sequencing and electron microscopy. The goal is to understand how well the dressings capture microbes, not to compare the dressings against each other.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- DACC-coated wound dressings (Sorbact Compress, Gel Dressing, Ribbon Gauze)
- What this could lead to
- If the dressings bind microbes as intended, this could support a drug-free way to manage hard-to-heal wounds and reduce reliance on antibiotics.
- What could go wrong
- This is a small, exploratory study with 30 participants and no comparison group, so it cannot prove that the dressings improve healing. The findings may not apply to all wound types or patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Able to read and understand the Subject Information and Informed Consent Form and provide meaningful informed consent 2. Due to start using one of the following dressings: Sorbact® Compress, Sorbact® Gel Dressing and Sorbact® Ribbon Gauze 3. Age ≥18 years 4. Presence of hard-to-heal wound for ≥6 weeks with no significant wound area reduction for the last 4 weeks confirmed by investigator/study nurse Exclusion Criteria: 1. Participating in another clinical investigation 2. Known allergy or sensitivity to any components of the allocated investigational device 3. Use of antimicrobial agent (e.g., silver- or iodine-containing dressings, or gels) during the last wo weeks 4. Use of a dressing from the Sorbact® range during the last two weeks 5. Subjects with any other condition that as judged by the investigator may make investigation procedures inappropriate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sahlgrenska University Hospital
RECRUITINGMölndal, 43143, Sweden
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Other studies related to the condition(s) this trial covers.
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- Zapping a leg nerve: can a wearable device help stubborn ulcers heal?
- Can a traditional herbal mix save limbs from diabetic ulcers?
- Blood tests may reveal hidden healing power of bone marrow stem cells