Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a simple sponge replace endoscopy for esophageal cancer screening?

NCT ID NCT06071845

Recruiting now Diagnosis Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial is testing a new, less invasive way to detect Barrett's esophagus, a condition that can lead to esophageal cancer. Participants swallow a capsule attached to a string that expands into a sponge in the stomach, collecting cells as it is pulled back up. The goal is to see if this Cytosponge device can accurately identify Barrett's esophagus compared to standard endoscopy, potentially making screening easier and more accessible for at-risk patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cytosponge device
What this could lead to
If successful, this could provide a simple, non-endoscopic screening test for Barrett's esophagus, enabling earlier detection and reducing the need for invasive procedures.
What could go wrong
This is an early-stage accuracy study (not a treatment trial), and the test may not be sensitive or specific enough to replace endoscopy. Results are compared to a previous device, so performance may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BARRETT ESOPHAGUS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Adenocarcinoma Of Esophagus Barrett esophagus esophageal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BARRETT ESOPHAGUS BARRETT'S ESOPHAGUS WITHOUT DYSPLASIA BARRETTS ESOPHAGUS WITH DYSPLASIA ESOPHAGEAL ADENOCARCINOMA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Long Island Jewish Medical Center | Northwell Health

    COMPLETED

    New Hyde Park, New York, 11040, United States

  • Mayo Clinic

    RECRUITING

    Scottsdale, Arizona, 85259, United States

    Contact Email: •••••@•••••

  • Mayo Clinic in Florida

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Email: •••••@•••••

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

  • Northwestern University

    TERMINATED

    Chicago, Illinois, 60611, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.