Blood test may reveal if chemo is working for pancreatic cancer patients

NCT ID NCT04616131

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study is testing whether a blood test that looks for tumor DNA (ctDNA) can help predict how well pancreatic cancer patients respond to chemotherapy. Researchers will track ctDNA levels before, during, and after treatment in 500 patients whose cancer has not spread. The goal is to see if the test can give doctors an early sign of whether the treatment is working.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test that helps doctors know sooner whether chemotherapy is working for pancreatic cancer patients.
What could go wrong
This is an observational study, not a treatment trial. It will not directly improve outcomes, and the blood test may not prove reliable enough for routine use.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Northwestern Medicine Cancer Center Delnor

    RECRUITING

    Geneva, Illinois, 60135, United States

  • Northwestern Medicine Cancer Center Kishwaukee

    RECRUITING

    DeKalb, Illinois, 60115, United States

  • Northwestern Medicine Cancer Center Warrenville

    RECRUITING

    Warrenville, Illinois, 60555, United States

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