New brain scan method could spot Alzheimer's sooner

NCT ID NCT05579236

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new way to analyze MRI brain scans, called Cortical Disarray Measurement (CDM), to see if it can help diagnose Alzheimer's disease more accurately. Researchers will follow 400 people with mild memory or thinking problems over time, comparing CDM results with standard memory tests. The goal is to find a better tool for early diagnosis, which could lead to earlier treatment and planning.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a more accurate and earlier diagnosis of Alzheimer's disease using a simple MRI scan.

What could go wrong

This is an observational study, not a treatment trial. The new technique may not prove reliable enough for widespread use, and results may take years to confirm.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction dementia disease neurodegenerative disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardiff and Vale University Health Board

    Cardiff, United Kingdom

  • Dorset Healthcare University NHS Foundation Trust

    Bournemouth, United Kingdom

  • University Hospital Southampton NHS Foundation Trust

    Southampton, Hampshire, SO16 6YD, United Kingdom