Which blood thinner is safer? major trial pits rivaroxaban against apixaban

NCT ID NCT04642430

Recruiting now Disease control Sponsor: Ottawa Hospital Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two blood thinners, rivaroxaban and apixaban, to see which causes less bleeding in people with atrial fibrillation (an irregular heartbeat). About 3,000 adults who need to start blood thinners will take one of the two drugs. The goal is to find which medication offers the best balance of stroke prevention and safety.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION

Contacts and locations

Locations

CHU de Quebec - Université Laval
NOT_YET_RECRUITING

Laval, Quebec, Canada
CISSS de l'Outaouais
RECRUITING

Gatineau, Quebec, J8T 4J3, Canada
Ciusss Nim
RECRUITING

Montreal, Quebec, H3L 1K5, Canada
Kingston General Hospital
RECRUITING

Kingston, Ontario, Canada
QEII Health Science Centre
RECRUITING

Halifax, Nova Scotia, Canada
The Ottawa Hospital - General Campus
RECRUITING

Ottawa, Ontario, K1H 8L6, Canada
University Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, Canada
Victoria Cardiac Arrhythmia Trials
RECRUITING

Victoria, British Columbia, V8Z 0B9, Canada

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