Knee surgery recovery boost? collagen supplement under study
NCT ID NCT05823727
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking a collagen peptide supplement before and after total knee replacement surgery can improve tissue healing, strength, and recovery. Researchers will measure changes in knee ligaments, bone density, and wound healing in 44 adults aged 50-75. Participants receive either collagen or a placebo for 24 weeks, with tissue samples collected during surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bovine collagen peptide supplement
What this could lead to
If it works, this could point toward a simple dietary supplement to improve recovery after knee replacement surgery.
What could go wrong
This is a small, early-stage study with only 44 participants, so results may not apply to everyone. The supplement may show no benefit over placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••