Global study reviews brain metastasis treatments in colorectal cancer patients

NCT ID NCT07448662

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study looks back at 700 patients from 15 hospitals in 2 countries to compare local treatments like surgery and radiation for brain metastases that spread from colorectal cancer. Researchers will track how long patients live and how long it takes for brain tumors to progress after treatment. The goal is to understand which strategies work best in real-world practice.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors choose the best local treatment (surgery or radiation) for brain metastases from colorectal cancer, potentially improving survival and quality of life.

What could go wrong

This is a retrospective observational study, not a controlled trial, so results may be influenced by patient selection and differences in care. It cannot prove one treatment is better than another.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer colonic neoplasm colorectal adenocarcinoma colorectal cancer colorectal neoplasm metastatic malignant neoplasm in the brain rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • A.S. Loginov Moscow Clinical Scientific Center

    Moscow, 111123, Russia

  • Blokhin's Russian Cancer Research Center

    Moscow, 115478, Russia

  • Federal Center of Neurosurgery

    Tyumen, 625062, Russia

  • Gamma Knife Center Moscow

    Moscow, 125047, Russia

  • Gomel Regional Clinical Oncology Dispensary (OKOD)

    Homyel, 246012, Belarus

  • Kaliningrad Regional Clinical Oncology Center

    Kaliningrad, 236016, Russia

  • Moscow Multidisciplinary Clinical Center "Kommunarka"

    Moscow, 117303, Russia

  • Moscow Regional Oncology Hospital No. 62

    Krasnogorsk, 143442, Russia

  • N.N. Burdenko National Medical Research Center of Neurosurgery

    Moscow, 125047, Russia

  • N.N. Petrov National Medical Research Center of Oncology

    Saint Petersburg, 197758, Russia

  • N.V. Sklifosovsky Research Institute for Emergency Medicine

    Moscow, 129090, Russia

  • OncoStop CyberKnife Center

    Moscow, 115478, Russia

  • P.A. Hertsen Moscow Oncology Research Institute

    Moscow, 125284, Russia

  • Republican Clinical Oncology Dispensary (RCOD)

    Ufa, 450054, Russia

  • S.S. Yudin City Clinical Hospital, Oncology Center No. 1

    Moscow, 115446, Russia