Could a 3-Month Low-Dose blood thinner replace lifelong pills after heart procedure?
NCT ID NCT07575867
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether people with atrial fibrillation can safely stop taking long-term blood thinners after a procedure that closes off a part of the heart called the left atrial appendage. Participants will get a reduced dose of the blood thinner apixaban for just 3 months after the procedure, then stop all blood thinners. The goal is to see if this approach is better than staying on standard-dose blood thinners forever, by comparing rates of bleeding, stroke, and other complications.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Apixaban (reduced dose) and left atrial appendage closure device (Watchman FLX or Amplatzer Amulet)
- What this could lead to
- If successful, this could offer a way for people with atrial fibrillation to stop taking lifelong blood thinners after a heart procedure, reducing bleeding risk while still preventing strokes.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less reliable. The reduced-dose apixaban is only given for 3 months, and there is a risk of stroke or device complications if blood thinners are stopped too soon.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Federal State Budgetary Institution National Medical Research Center for Therapy and Preventive Medicine of the Ministry of Healthсare of the Russian Federation
RECRUITINGMoscow, 101990, Russia
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