Fertility drug trial for men with no sperm pulled before it began
NCT ID NCT03615547
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aimed to see if the drug clomiphene citrate could help men with a condition called non-obstructive azoospermia, where the body produces little to no sperm. The plan was to give the drug or a placebo for nine months, then check if sperm could be found in the semen or through a second surgical extraction. However, the trial was withdrawn before enrolling any participants, so we don't know if the drug would have helped.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Clomiphene citrate
What this could lead to
If it had worked, this could have offered men with non-obstructive azoospermia a better chance of fathering their own biological children through a second sperm extraction procedure.
What could go wrong
The trial was withdrawn before any participants were enrolled, so no results are available. Previous studies on hormonal therapy for this condition have been small and inconsistent.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant
Bron, France