Could a plant extract make rectal cancer treatment easier to tolerate?
NCT ID NCT05856305
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding chlorophyllin, a natural plant extract, to standard chemoradiation can reduce side effects like diarrhea, bladder irritation, and low blood counts in people with locally advanced rectal cancer. About 76 adults will receive either chlorophyllin or a placebo alongside their cancer therapy. The goal is to see if chlorophyllin helps patients feel better and increases the chance of avoiding surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Chlorophyllin (a natural plant extract)
What this could lead to
If it works, this could offer a simple way to reduce painful side effects from cancer treatment and help more patients avoid surgery.
What could go wrong
This is a small, early-phase trial with only 76 participants. The benefit may be small or not seen at all, and chlorophyllin might not reduce side effects significantly.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RECTAL NEOPLASMS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Tata Memorial Hospital
Mumbai, Maharashtra, 400012, India