Could a plant extract make rectal cancer treatment easier to tolerate?

NCT ID NCT05856305

Ongoing Symptom relief Sponsor: Tata Memorial Centre Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding chlorophyllin, a natural plant extract, to standard chemoradiation can reduce side effects like diarrhea, bladder irritation, and low blood counts in people with locally advanced rectal cancer. About 76 adults will receive either chlorophyllin or a placebo alongside their cancer therapy. The goal is to see if chlorophyllin helps patients feel better and increases the chance of avoiding surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Chlorophyllin (a natural plant extract)
What this could lead to: If it works, this could offer a simple way to reduce painful side effects from cancer treatment and help more patients avoid surgery.
What could go wrong: This is a small, early-phase trial with only 76 participants. The benefit may be small or not seen at all, and chlorophyllin might not reduce side effects significantly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL NEOPLASMS

Contacts and locations

Locations

Tata Memorial Hospital

Mumbai, Maharashtra, 400012, India

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