Brain pacemaker gets a software upgrade to fight freezing gait

NCT ID NCT05292794

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a software called CereGate that fine-tunes an already-implanted deep brain stimulator to reduce freezing of gait in Parkinson's disease. About 41 participants will have their stimulator adjusted using the software. The goal is to see if this extra tuning can make walking smoother and safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CereGate Software (a software that adjusts deep brain stimulation settings)
What this could lead to
If it works, this could offer a new way to reduce freezing of gait episodes in people with Parkinson's who already have a deep brain stimulator.
What could go wrong
This is a small, early study with only 41 participants. It is testing a software modification, not a new drug, so the benefits may be modest or not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Gait Disorders, Neurologic Mobility Limitation Motor Disorders Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kaiser Permanente, KPNC Comprehensive Movement Disorders Program

    RECRUITING

    Redwood City, California, 94063, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

  • University of Washington

    RECRUITING

    Seattle, Washington, 98195, United States

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Wake Forest University

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

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