Could a simple calcium shot save lives after trauma?

NCT ID NCT05958342

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tests whether giving calcium before reaching the hospital and vasopressin early in the hospital can reduce deaths in people with severe bleeding from injury. About 1050 adults at risk of hemorrhagic shock will be randomly assigned to receive these treatments or placebos. The main goal is to see if more people survive to 30 days.

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Conditions

The condition(s) this trial relates to.

diabetes insipidus Hemorrhage injury Shock, Hemorrhagic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Allegheny Health Network

    RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

  • Chandler Regional Medical Center

    RECRUITING

    Chandler, Arizona, 85224, United States

  • Denver Health Medical Center

    RECRUITING

    Denver, Colorado, 80204, United States

  • Hennepin County Medical Center

    RECRUITING

    Minneapolis, Minnesota, 55415, United States

  • Mount Carmel East Hospital

    RECRUITING

    Columbus, Ohio, 43213, United States

  • Texas Tech University Health Sciences Center

    RECRUITING

    Lubbock, Texas, 79430, United States

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • University of Arizona

    RECRUITING

    Tucson, Arizona, 85724, United States

  • University of Arkansas for Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

  • University of Maryland, Baltimore

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

  • University of Missouri Health Care

    RECRUITING

    Columbia, Missouri, 65202, United States

  • University of New Mexico

    RECRUITING

    Albuquerque, New Mexico, 87131, United States

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Washington Harborview Medical Center

    RECRUITING

    Seattle, Washington, 98104, United States

  • Zuckerberg San Francisco General Hospital and Trauma Center at University of California, San Francisco

    RECRUITING

    San Francisco, California, 94110, United States

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