Heart-Brain link: major study seeks hidden causes of learning delays in children with heart defects

NCT ID NCT06442592

Recruiting now Knowledge-focused Sponsor: Nantes University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow over 1,200 children aged 3 to 11 who were born with critical heart defects and had heart surgery in their first three months. Researchers want to find out how many of these children develop learning, attention, or behavioral problems, and why. They will use blood tests and brain assessments to look for genetic and other factors that might link heart and brain development. The goal is to catch these issues early and improve support for affected children and families.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to earlier detection and better support for children with heart defects who are at risk for learning or behavioral challenges.
What could go wrong: This is an observational study, not a treatment trial. It will not directly change how children are treated, and results may take years to influence care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease neurodevelopmental disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONGENITAL HEART DEFECTS NEURODEVELOPMENTAL DISORDER

Contacts and locations

Locations

CHU Angers
RECRUITING

Angers, Maine-et-Loire, 49000, France
CHU Nantes
RECRUITING

Nantes, Loire-Atlantique, 44000, France
CHU Rennes
RECRUITING

Rennes, Brittany Region, 35000, France
CHU Tours
RECRUITING

Tours, Val de Loire, 37000, France
Chu Brest
RECRUITING

Brest, Brittany Region, 29200, France

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