Heart-Brain link: major study seeks hidden causes of learning delays in children with heart defects

NCT ID NCT06442592

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will follow over 1,200 children aged 3 to 11 who were born with critical heart defects and had heart surgery in their first three months. Researchers want to find out how many of these children develop learning, attention, or behavioral problems, and why. They will use blood tests and brain assessments to look for genetic and other factors that might link heart and brain development. The goal is to catch these issues early and improve support for affected children and families.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to earlier detection and better support for children with heart defects who are at risk for learning or behavioral challenges.

What could go wrong

This is an observational study, not a treatment trial. It will not directly change how children are treated, and results may take years to influence care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital heart disease neurodevelopmental disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Angers

    RECRUITING

    Angers, Maine-et-Loire, 49000, France

    Contact

  • CHU Nantes

    RECRUITING

    Nantes, Loire-Atlantique, 44000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU Rennes

    RECRUITING

    Rennes, Brittany Region, 35000, France

    Contact

  • CHU Tours

    RECRUITING

    Tours, Val de Loire, 37000, France

    Contact

  • Chu Brest

    RECRUITING

    Brest, Brittany Region, 29200, France

    Contact Email: •••••@•••••

    Contact