Partial thymectomy may shield infant immunity after heart surgery

NCT ID NCT07019857

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at infants having heart surgery, where the thymus gland is often fully removed to access the heart. The thymus helps build the immune system early in life. Researchers want to see if removing only part of the thymus keeps the immune system stronger and reduces infections. They will compare blood tests and infection records over one year in three groups: complete removal, partial removal, and no removal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could guide surgeons to preserve part of the thymus during infant heart surgery, potentially reducing infection risks and improving immune health.

What could go wrong

This is a small, single-center observational study, not a treatment trial. It only measures immune markers and infection rates, so it cannot prove that partial thymectomy directly causes better outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital heart disease inborn error of immunity Infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • CHU de Nantes

    NOT_YET_RECRUITING

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Chu de Nantes

    RECRUITING

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••