Early trial tests cancer drug combo for patients with organ damage
NCT ID NCT01366144
Summary
This early-stage study aims to find safe doses of a three-drug combination for treating advanced solid tumors in patients who also have kidney or liver problems. Researchers are testing a new drug called veliparib, given with two standard chemotherapy drugs, to see how the body processes it and what side effects occur in people with organ dysfunction. The goal is to provide dosing guidance for future use in this specific patient group.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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City of Hope South Pasadena
South Pasadena, California, 91030, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Montefiore Medical Center - Moses Campus
The Bronx, New York, 10467, United States
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Montefiore Medical Center-Weiler Hospital
The Bronx, New York, 10461, United States
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Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, 17033-0850, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792, United States
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Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
Conditions
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