Urine test may predict kidney recovery in septic shock patients

NCT ID NCT03472079

Completed Diagnosis Sponsor: Centre Hospitalier Universitaire, Amiens Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a urine test measuring two proteins (TIMP2 and IGFBP7) can tell which septic shock patients will recover normal kidney function within 72 hours. Researchers analyzed data from 77 patients in French ICUs. The goal is to help doctors decide who needs aggressive kidney support and who may recover on their own.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: urine test for TIMP2*IGFBP7 levels
What this could lead to: If successful, this test could help doctors quickly identify which septic shock patients are likely to recover kidney function on their own, guiding early treatment decisions.
What could go wrong: This is a small, retrospective study (77 patients) looking back at past data, so results may not apply to all patients. The test is not a treatment and may not be accurate enough for routine use.

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Conditions

The condition(s) this trial relates to.

acute kidney injury toxic shock syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEPTIC SHOCK

Contacts and locations

Locations

CHU Amiens-Picardie

Amiens, 80000, France

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