Can learning about pain boost exercise benefits for arthritic knees?

NCT ID NCT07565298

Completed Symptom relief Sponsor: Pontificia Universidad Catolica de Chile Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether adding group-based pain neuroscience education (PNE) to a community exercise program helps older women with knee osteoarthritis. Nineteen women aged 60+ were randomly assigned to 10 weeks of exercise plus PNE or exercise alone. Researchers measured daily function, pain, and knowledge about pain. The goal was to see if this combined approach is feasible and offers extra benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pain neuroscience education (PNE) plus exercise
What this could lead to: If it works, this approach could offer a simple, non-drug way to help older women with knee osteoarthritis feel better and move more easily.
What could go wrong: This was a very small pilot study with only 19 participants, so results may not apply to everyone. The added benefit of PNE over exercise alone is still uncertain.

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Conditions

The condition(s) this trial relates to.

Motor Activity osteoarthritis, knee Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISABILITY KNEE OSTEOARTHRITIS OLDER WOMEN PAIN

Contacts and locations

Locations

Pontificia Universidad Católica de Chile

Santiago, Chile

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