New drug aims to cut bleeding in knee replacements
NCT ID NCT07127042
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests an experimental drug called BT-114143 to see if it can reduce blood loss during knee replacement surgery better than a standard treatment. About 270 adults with osteoarthritis who need a knee replacement will take part. Participants will receive either a high or low dose of BT-114143 or the standard drug tranexamic acid before and after surgery, and their total blood loss will be measured.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Orthopaedics, West China Hospital, SIchuan University
RECRUITINGChengdu, Si'Chuan, 37 Guoxuexiang, China
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