New drug aims to cut bleeding in knee replacement

NCT ID NCT07127042

First seen Jan 10, 2026 · Last updated May 16, 2026 · Updated 19 times

Summary

This study tests an experimental drug called BT-114143 to see if it can reduce blood loss during knee replacement surgery better than the current standard treatment. About 270 adults having knee replacement will receive either a high or low dose of BT-114143 or tranexamic acid. The main goal is to measure total blood loss around the time of surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Orthopaedics, West China Hospital, SIchuan University

    RECRUITING

    Chengdu, Si'Chuan, 37 Guoxuexiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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